STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFM53263.12-methylaconitate cis-trans isomerase. (395 aa)    
Predicted Functional Partners:
SFM53243.1
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 
 0.999
SFM19955.1
Aconitase; Belongs to the aconitase/IPM isomerase family.
    
 0.954
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
  
 0.924
SFM10732.1
Adenylyltransferase and sulfurtransferase.
     
 0.847
SFM53228.1
2-methylcitrate synthase; Belongs to the citrate synthase family.
 
  
 0.822
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
     
 0.783
SFM53182.1
Transcriptional regulator, GntR family; Manually curated.
 
  
 0.577
SFM24719.1
Citrate synthase; Belongs to the citrate synthase family.
  
  
 0.481
mhpB
2,3-dihydroxyphenylpropionate 1,2-dioxygenase; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family.
    
 0.469
SFM75769.1
Uncharacterized membrane protein YGL010W.
  
     0.445
Your Current Organism:
Marinobacter zhejiangensis
NCBI taxonomy Id: 488535
Other names: CGMCC 1.7061, JCM 15156, M. zhejiangensis, Marinobacter sp. CN74, Marinobacter zhejiangensis Huo et al. 2008, strain CN74
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