STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADE38680.1Hypothetical protein. (101 aa)    
Predicted Functional Partners:
hisI
phosphoribosyl-AMP cyclohydrolase HisIE; In the N-terminal section; belongs to the PRA-CH family.
     
 0.582
hisG
ATP phosphoribosyltransferase HisG; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
       0.581
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
       0.578
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
       0.578
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
       0.578
hisC
Histidinol-phosphate aminotransferase; Belongs to the imidazoleglycerol-phosphate dehydratase family.
       0.578
ADE38687.1
Hypothetical protein.
       0.545
ADE38732.1
Acetyltransferase, GNAT family.
  
  
 0.527
ADE38819.1
Aminotransferase class-III.
  
  
 0.516
ADE38488.1
Putative transcriptional regulator.
  
    0.489
Your Current Organism:
Puniceispirillum marinum
NCBI taxonomy Id: 488538
Other names: C. Puniceispirillum marinum IMCC1322, Candidatus Puniceispirillum marinum IMCC1322, Candidatus Puniceispirillum marinum str. IMCC1322, Candidatus Puniceispirillum marinum strain IMCC1322, alpha proteobacterium IMCC1322
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