STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAHydrogenase nickel incorporation protein HypA. (80 aa)    
Predicted Functional Partners:
hypB
Hydrogenase isoenzymes nickel incorporation protein HypB.
 
 
 0.990
KHS49512.1
Periplasmic [NiFeSe] hydrogenase large subunit.
 
 
 0.990
KHS49504.1
Nitrogen-fixing NifU domain-containing protein.
 
   
 0.947
KHS49507.1
Hypothetical protein.
 
     0.946
hypC
Hydrogenase isoenzymes formation protein HypC.
 
  
 0.945
KHS49503.1
NHL repeat protein.
 
     0.941
KHS49509.1
Hypothetical protein.
 
  
 0.925
hypD
Hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
  
 0.911
hypF
Carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
   
 0.907
hypE
Hydrogenase isoenzymes formation protein HypE.
 
  
 0.895
Your Current Organism:
Novosphingobium subterraneum
NCBI taxonomy Id: 48936
Other names: ATCC 700279, CIP 105153, DSM 12447, IFO 16086, N. subterraneum, NBRC 16086, Novosphingobium subterraneae, SMCC B0478, Sphingomonas subterrae, Sphingomonas subterranea, Sphingomonas subterraneae, strain B0478
Server load: low (14%) [HD]