Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (268 aa)    
Predicted Functional Partners:
KHS45859.1
Proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 0.948
proB
Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 
 0.879
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.874
KHS49240.1
2OG-Fe(II) oxygenase.
    
  0.862
KHS43272.1
2OG-Fe(II) oxygenase.
     
  0.862
KHS48362.1
Aspartate racemase.
     
  0.737
KHS44507.1
Ornithine cyclodeaminase.
   
 
 0.709
KHS46475.1
Hypothetical protein.
       0.631
KHS45915.1
CopG/DNA-binding domain-containing protein.
     
 0.625
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.607
Your Current Organism:
Novosphingobium subterraneum
NCBI taxonomy Id: 48936
Other names: ATCC 700279, CIP 105153, DSM 12447, IFO 16086, N. subterraneum, NBRC 16086, Novosphingobium subterraneae, SMCC B0478, Sphingomonas subterrae, Sphingomonas subterranea, Sphingomonas subterraneae, strain B0478
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