Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KHS46520.13-hydroxyisobutyrate dehydrogenase. (313 aa)    
Predicted Functional Partners:
KHS46521.1
Amidohydrolase.
    
  0.888
KHS42665.1
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
  
  
 
0.888
KHS44152.1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
  0.868
KHS45043.1
Hydroxypyruvate isomerase; Belongs to the hyi family.
 
 
 0.835
KHS42672.1
Methylmalonate-semialdehyde dehydrogenase.
  
 
  0.823
KHS48832.1
Carbamoyl-phosphate synthase L chain, ATP-binding.
   
 
  0.777
KHS49189.1
Glycolate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.773
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.766
KHS48826.1
Carboxyl transferase.
     
  0.765
KHS48985.1
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.753
Your Current Organism:
Novosphingobium subterraneum
NCBI taxonomy Id: 48936
Other names: ATCC 700279, CIP 105153, DSM 12447, IFO 16086, N. subterraneum, NBRC 16086, Novosphingobium subterraneae, SMCC B0478, Sphingomonas subterrae, Sphingomonas subterranea, Sphingomonas subterraneae, strain B0478
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