STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KHS46520.13-hydroxyisobutyrate dehydrogenase. (313 aa)    
Predicted Functional Partners:
KHS42665.1
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
  
  
 
0.925
KHS44152.1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
  0.912
KHS46521.1
Amidohydrolase.
    
  0.895
KHS42672.1
Methylmalonate-semialdehyde dehydrogenase.
  
 
  0.861
KHS48832.1
Carbamoyl-phosphate synthase L chain, ATP-binding.
  
 
  0.842
KHS45043.1
Hydroxypyruvate isomerase; Belongs to the hyi family.
 
 
 0.841
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
  0.820
KHS44119.1
CoA-binding protein.
    
  0.792
KHS49189.1
Glycolate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.778
KHS46514.1
Aldehyde dehydrogenase.
   
 
  0.737
Your Current Organism:
Novosphingobium subterraneum
NCBI taxonomy Id: 48936
Other names: ATCC 700279, CIP 105153, DSM 12447, IFO 16086, N. subterraneum, NBRC 16086, Novosphingobium subterraneae, SMCC B0478, Sphingomonas subterrae, Sphingomonas subterranea, Sphingomonas subterraneae, strain B0478
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