Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KHS45862.1Fumarate reductase/succinate dehydrogenase flavoprotein-like protein. (551 aa)    
Predicted Functional Partners:
KHS47745.1
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.986
sdhB
Succinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.963
KHS46796.1
Succinate dehydrogenase subunit C.
  
 0.962
KHS46797.1
Succinate dehydrogenase subunit D.
  
 0.931
KHS46055.1
Nuclear transport factor 2.
  
  
  0.891
KHS43424.1
Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
 0.880
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.866
KHS46809.1
Pyruvate flavodoxin/ferredoxin oxidoreductase-like protein.
  
 
 0.865
KHS49176.1
NADH dehydrogenase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
   
 
 0.851
KHS46002.1
Rieske (2Fe-2S) domain-containing protein.
  
  
  0.844
Your Current Organism:
Novosphingobium subterraneum
NCBI taxonomy Id: 48936
Other names: ATCC 700279, CIP 105153, DSM 12447, IFO 16086, N. subterraneum, NBRC 16086, Novosphingobium subterraneae, SMCC B0478, Sphingomonas subterrae, Sphingomonas subterranea, Sphingomonas subterraneae, strain B0478
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