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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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[Homology]
Score
KHS45009.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (479 aa)    
Predicted Functional Partners:
KHS48249.1
Branched-chain alpha-keto acid dehydrogenase E1 component.
 
 0.989
KHS45007.1
Pyruvate dehydrogenase E1 component subunit alpha.
 
 0.988
KHS45008.1
Pyruvate dehydrogenase E1 component subunit beta.
 
 0.988
KHS48526.1
Dihydrolipoamide dehydrogenase.
 0.980
pdhA
Pyruvate dehydrogenase (lipoamide); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.978
sucA
2-oxoglutarate dehydrogenase E1.
 
 0.976
KHS43212.1
Dihydrolipoamide dehydrogenase.
 0.967
KHS48433.1
Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
0.956
KHS48493.1
Branched-chain alpha-keto acid dehydrogenase E1 component; Overlaps another CDS with the same product name.
 
 0.945
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.939
Your Current Organism:
Novosphingobium subterraneum
NCBI taxonomy Id: 48936
Other names: ATCC 700279, CIP 105153, DSM 12447, IFO 16086, N. subterraneum, NBRC 16086, Novosphingobium subterraneae, SMCC B0478, Sphingomonas subterrae, Sphingomonas subterranea, Sphingomonas subterraneae, strain B0478
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