Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KHS44512.1Aldehyde dehydrogenase. (486 aa)    
Predicted Functional Partners:
KHS44511.1
FAD dependent oxidoreductase.
 
 
  0.860
KHS43441.1
Glutamate synthase (NADH) large subunit.
  
 
 0.824
KHS44502.1
Haloacid dehalogenase.
 
  
  0.820
KHS45859.1
Proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
 0.777
KHS44513.1
FAD dependent oxidoreductase.
 
 
  0.759
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.735
KHS42665.1
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
  
 
 0.724
KHS46520.1
3-hydroxyisobutyrate dehydrogenase.
   
 
  0.723
KHS43440.1
Glutamate synthase (NADH) small subunit.
    
  0.721
KHS45867.1
Putative allophanate hydrolase subunit 2/urea carboxylase.
     
 0.716
Your Current Organism:
Novosphingobium subterraneum
NCBI taxonomy Id: 48936
Other names: ATCC 700279, CIP 105153, DSM 12447, IFO 16086, N. subterraneum, NBRC 16086, Novosphingobium subterraneae, SMCC B0478, Sphingomonas subterrae, Sphingomonas subterranea, Sphingomonas subterraneae, strain B0478
Server load: medium (42%) [HD]