Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KHS44513.1FAD dependent oxidoreductase. (441 aa)    
Predicted Functional Partners:
thiG
Bifunctional sulfur carrier protein/thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 
 0.948
KHS43441.1
Glutamate synthase (NADH) large subunit.
  
 
 0.898
KHS44509.1
GCN5-like N-acetyltransferase.
 
     0.881
KHS44514.1
GCN5-like N-acetyltransferase.
 
     0.873
KHS44502.1
Haloacid dehalogenase.
 
  
  0.865
KHS44503.1
Extracellular solute-binding protein.
 
     0.838
KHS42355.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase.
   
 0.819
KHS44553.1
Haloacid dehalogenase.
 
  
  0.809
KHS44511.1
FAD dependent oxidoreductase.
 
   
0.808
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.789
Your Current Organism:
Novosphingobium subterraneum
NCBI taxonomy Id: 48936
Other names: ATCC 700279, CIP 105153, DSM 12447, IFO 16086, N. subterraneum, NBRC 16086, Novosphingobium subterraneae, SMCC B0478, Sphingomonas subterrae, Sphingomonas subterranea, Sphingomonas subterraneae, strain B0478
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.