node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aco1 | aco2 | O13966 | Q9P7D4 | Aconitate hydratase, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate, a step in the citric acid cycle; Belongs to the aconitase/IPM isomerase family. | Homocitrate dehydratase, mitochondrial; Catalyzes the reversible dehydration of (R)-homocitrate to cis-homoaconitate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. | 0.660 |
aco1 | cit1 | O13966 | Q10306 | Aconitate hydratase, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate, a step in the citric acid cycle; Belongs to the aconitase/IPM isomerase family. | Probable citrate synthase, mitochondrial; Belongs to the citrate synthase family. | 0.998 |
aco1 | icl1 | O13966 | Q9P6J1 | Aconitate hydratase, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate, a step in the citric acid cycle; Belongs to the aconitase/IPM isomerase family. | Mitochondrial 2-methylisocitrate lyase; Catalyzes the formation of pyruvate and succinate from 2- methylisocitrate during the metabolism of endogenous propionyl-CoA. Does not act on isocitrate (By similarity); Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | 0.980 |
aco1 | nep2 | O13966 | O13612 | Aconitate hydratase, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate, a step in the citric acid cycle; Belongs to the aconitase/IPM isomerase family. | NEDD8-specific protease 2; Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as the pcu1, pcu2 and pcu4 cullins and other proteins (By similarity). Has a role in meiosis; Belongs to the peptidase C48 family. | 0.646 |
aco2 | aco1 | Q9P7D4 | O13966 | Homocitrate dehydratase, mitochondrial; Catalyzes the reversible dehydration of (R)-homocitrate to cis-homoaconitate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. | Aconitate hydratase, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate, a step in the citric acid cycle; Belongs to the aconitase/IPM isomerase family. | 0.660 |
aco2 | cit1 | Q9P7D4 | Q10306 | Homocitrate dehydratase, mitochondrial; Catalyzes the reversible dehydration of (R)-homocitrate to cis-homoaconitate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. | Probable citrate synthase, mitochondrial; Belongs to the citrate synthase family. | 0.938 |
aco2 | icl1 | Q9P7D4 | Q9P6J1 | Homocitrate dehydratase, mitochondrial; Catalyzes the reversible dehydration of (R)-homocitrate to cis-homoaconitate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. | Mitochondrial 2-methylisocitrate lyase; Catalyzes the formation of pyruvate and succinate from 2- methylisocitrate during the metabolism of endogenous propionyl-CoA. Does not act on isocitrate (By similarity); Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | 0.812 |
aco2 | lys2 | Q9P7D4 | Q9UT74 | Homocitrate dehydratase, mitochondrial; Catalyzes the reversible dehydration of (R)-homocitrate to cis-homoaconitate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. | Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. | 0.517 |
aco2 | nep2 | Q9P7D4 | O13612 | Homocitrate dehydratase, mitochondrial; Catalyzes the reversible dehydration of (R)-homocitrate to cis-homoaconitate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. | NEDD8-specific protease 2; Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as the pcu1, pcu2 and pcu4 cullins and other proteins (By similarity). Has a role in meiosis; Belongs to the peptidase C48 family. | 0.644 |
cit1 | aco1 | Q10306 | O13966 | Probable citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Aconitate hydratase, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate, a step in the citric acid cycle; Belongs to the aconitase/IPM isomerase family. | 0.998 |
cit1 | aco2 | Q10306 | Q9P7D4 | Probable citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Homocitrate dehydratase, mitochondrial; Catalyzes the reversible dehydration of (R)-homocitrate to cis-homoaconitate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. | 0.938 |
cit1 | icl1 | Q10306 | Q9P6J1 | Probable citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Mitochondrial 2-methylisocitrate lyase; Catalyzes the formation of pyruvate and succinate from 2- methylisocitrate during the metabolism of endogenous propionyl-CoA. Does not act on isocitrate (By similarity); Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | 0.959 |
cit1 | lys2 | Q10306 | Q9UT74 | Probable citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. | 0.841 |
cit1 | mtf1 | Q10306 | Q9US51 | Probable citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Mitochondrial transcription factor 1; Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. | 0.840 |
cit1 | nep2 | Q10306 | O13612 | Probable citrate synthase, mitochondrial; Belongs to the citrate synthase family. | NEDD8-specific protease 2; Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as the pcu1, pcu2 and pcu4 cullins and other proteins (By similarity). Has a role in meiosis; Belongs to the peptidase C48 family. | 0.569 |
gpi12 | nep2 | Q9HDW9 | O13612 | Probable N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol (By similarity); Belongs to the PIGL family. | NEDD8-specific protease 2; Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as the pcu1, pcu2 and pcu4 cullins and other proteins (By similarity). Has a role in meiosis; Belongs to the peptidase C48 family. | 0.647 |
icl1 | aco1 | Q9P6J1 | O13966 | Mitochondrial 2-methylisocitrate lyase; Catalyzes the formation of pyruvate and succinate from 2- methylisocitrate during the metabolism of endogenous propionyl-CoA. Does not act on isocitrate (By similarity); Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Aconitate hydratase, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate, a step in the citric acid cycle; Belongs to the aconitase/IPM isomerase family. | 0.980 |
icl1 | aco2 | Q9P6J1 | Q9P7D4 | Mitochondrial 2-methylisocitrate lyase; Catalyzes the formation of pyruvate and succinate from 2- methylisocitrate during the metabolism of endogenous propionyl-CoA. Does not act on isocitrate (By similarity); Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Homocitrate dehydratase, mitochondrial; Catalyzes the reversible dehydration of (R)-homocitrate to cis-homoaconitate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. | 0.812 |
icl1 | cit1 | Q9P6J1 | Q10306 | Mitochondrial 2-methylisocitrate lyase; Catalyzes the formation of pyruvate and succinate from 2- methylisocitrate during the metabolism of endogenous propionyl-CoA. Does not act on isocitrate (By similarity); Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Probable citrate synthase, mitochondrial; Belongs to the citrate synthase family. | 0.959 |
icl1 | lys2 | Q9P6J1 | Q9UT74 | Mitochondrial 2-methylisocitrate lyase; Catalyzes the formation of pyruvate and succinate from 2- methylisocitrate during the metabolism of endogenous propionyl-CoA. Does not act on isocitrate (By similarity); Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. | 0.659 |