STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sec6Exocyst complex subunit sec6; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane (752 aa)    
Predicted Functional Partners:
sec10
Putative exocyst complex subunit sec10; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane
   
 0.999
exo84
Putative exocyst complex subunit exo84; Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Plays a role in both the assembly of the exocyst and the polarization of this complex to specific sites of the plasma membrane for exocytosis. Also involved in assembly of the spliceosome (By similarity)
   
 0.999
exo70
Putative exocyst complex subunit exo70; Required for exocytosis
   
 0.999
sec15
Putative exocyst complex subunit sec15; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane
   
 0.999
sec8
Exocyst complex subunit sec8; Component of the exocyst complex involved in the delivery of secretory vesicles to the plasma membrane. Also required for polarized cell growth and division septum assembly. The exocyst complex plays an important role in the targeting of rho3, as well as the two main hydrolases required for cell separation, eng1 and agn1, to the cell wall surrounding the septum before cell separation begins
   
 0.999
ypt2
Ras-related protein rab-8a; Protein transport. Probably involved in vesicular traffic (By similarity)
   
 
 0.996
sec1
Putative snare-binding protein sec1; Involved in the final stage of protein secretion
   
 
 0.988
pof6
F-box protein pof6; Together with skp1, essential for septum processing and cell separation
   
 0.985
sec9
Protein transport protein sec9; Has a role in cell separation, a final step of cytokinesis and in the assembly of the forespore membrane. May have a role in the transport of secretory proteins to these growing sites
   
 
 0.982
sec5
Putative exocyst complex subunit sec5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane
   
 
 0.963
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 4896
Other names: CBS 356, CCRC 21461, DBVPG 6277, JCM 8274, MUCL 30245, NRRL Y-12796, S. pombe, Schizosaccharomyces malidevorans, fission yeast
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