node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEQ24089.1 | SEQ52386.1 | SAMN04488038_1058 | SAMN04488038_107166 | Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain. | Membrane-bound lytic murein transglycosylase D. | 0.720 |
SEQ24089.1 | anmK | SAMN04488038_1058 | SAMN04488038_1059 | Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.859 |
SEQ24089.1 | mltG | SAMN04488038_1058 | SAMN04488038_10919 | Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain. | UPF0755 protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.514 |
SEQ24089.1 | tyrS | SAMN04488038_1058 | SAMN04488038_1057 | Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. | 0.591 |
SEQ24548.1 | SEQ52386.1 | SAMN04488038_10521 | SAMN04488038_107166 | AmpD protein. | Membrane-bound lytic murein transglycosylase D. | 0.439 |
SEQ24548.1 | anmK | SAMN04488038_10521 | SAMN04488038_1059 | AmpD protein. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.562 |
SEQ24548.1 | nagZ | SAMN04488038_10521 | SAMN04488038_108129 | AmpD protein. | beta-N-acetylhexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.471 |
SEQ52386.1 | SEQ24089.1 | SAMN04488038_107166 | SAMN04488038_1058 | Membrane-bound lytic murein transglycosylase D. | Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain. | 0.720 |
SEQ52386.1 | SEQ24548.1 | SAMN04488038_107166 | SAMN04488038_10521 | Membrane-bound lytic murein transglycosylase D. | AmpD protein. | 0.439 |
SEQ52386.1 | SEQ99961.1 | SAMN04488038_107166 | SAMN04488038_113162 | Membrane-bound lytic murein transglycosylase D. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.436 |
SEQ52386.1 | anmK | SAMN04488038_107166 | SAMN04488038_1059 | Membrane-bound lytic murein transglycosylase D. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.411 |
SEQ52386.1 | mltG | SAMN04488038_107166 | SAMN04488038_10919 | Membrane-bound lytic murein transglycosylase D. | UPF0755 protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.569 |
SEQ52386.1 | nagZ | SAMN04488038_107166 | SAMN04488038_108129 | Membrane-bound lytic murein transglycosylase D. | beta-N-acetylhexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.533 |
SEQ99961.1 | SEQ52386.1 | SAMN04488038_113162 | SAMN04488038_107166 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Membrane-bound lytic murein transglycosylase D. | 0.436 |
SEQ99961.1 | anmK | SAMN04488038_113162 | SAMN04488038_1059 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.513 |
SEQ99961.1 | mltG | SAMN04488038_113162 | SAMN04488038_10919 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | UPF0755 protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.516 |
anmK | SEQ24089.1 | SAMN04488038_1059 | SAMN04488038_1058 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain. | 0.859 |
anmK | SEQ24548.1 | SAMN04488038_1059 | SAMN04488038_10521 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | AmpD protein. | 0.562 |
anmK | SEQ52386.1 | SAMN04488038_1059 | SAMN04488038_107166 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Membrane-bound lytic murein transglycosylase D. | 0.411 |
anmK | SEQ99961.1 | SAMN04488038_1059 | SAMN04488038_113162 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.513 |