node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHG42341.1 | SHG66251.1 | SAMN04488068_0117 | SAMN04488068_0990 | His Kinase A (phospho-acceptor) domain-containing protein. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.844 |
SHG42341.1 | SHG67876.1 | SAMN04488068_0117 | SAMN04488068_1063 | His Kinase A (phospho-acceptor) domain-containing protein. | GAF domain-containing protein. | 0.999 |
SHG42341.1 | SHH20993.1 | SAMN04488068_0117 | SAMN04488068_2882 | His Kinase A (phospho-acceptor) domain-containing protein. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.901 |
SHG42341.1 | nadE | SAMN04488068_0117 | SAMN04488068_1371 | His Kinase A (phospho-acceptor) domain-containing protein. | NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.667 |
SHG42341.1 | nudJ | SAMN04488068_0117 | SAMN04488068_2312 | His Kinase A (phospho-acceptor) domain-containing protein. | ADP-ribose pyrophosphatase YjhB, NUDIX family; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.799 |
SHG66251.1 | SHG42341.1 | SAMN04488068_0990 | SAMN04488068_0117 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | His Kinase A (phospho-acceptor) domain-containing protein. | 0.844 |
SHG66251.1 | SHG67876.1 | SAMN04488068_0990 | SAMN04488068_1063 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | GAF domain-containing protein. | 0.828 |
SHG66251.1 | SHH20993.1 | SAMN04488068_0990 | SAMN04488068_2882 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.566 |
SHG66251.1 | nudJ | SAMN04488068_0990 | SAMN04488068_2312 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | ADP-ribose pyrophosphatase YjhB, NUDIX family; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.813 |
SHG67876.1 | SHG42341.1 | SAMN04488068_1063 | SAMN04488068_0117 | GAF domain-containing protein. | His Kinase A (phospho-acceptor) domain-containing protein. | 0.999 |
SHG67876.1 | SHG66251.1 | SAMN04488068_1063 | SAMN04488068_0990 | GAF domain-containing protein. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.828 |
SHG67876.1 | SHH20993.1 | SAMN04488068_1063 | SAMN04488068_2882 | GAF domain-containing protein. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.818 |
SHG67876.1 | nudJ | SAMN04488068_1063 | SAMN04488068_2312 | GAF domain-containing protein. | ADP-ribose pyrophosphatase YjhB, NUDIX family; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.792 |
SHH05171.1 | SHH05195.1 | SAMN04488068_2309 | SAMN04488068_2310 | General secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | General secretion pathway protein M; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | 0.999 |
SHH05171.1 | SHH05215.1 | SAMN04488068_2309 | SAMN04488068_2311 | General secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | Type II secretion system (T2SS), protein N. | 0.837 |
SHH05171.1 | mnmA | SAMN04488068_2309 | SAMN04488068_2313 | General secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | tRNA-specific 2-thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.804 |
SHH05171.1 | nudJ | SAMN04488068_2309 | SAMN04488068_2312 | General secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | ADP-ribose pyrophosphatase YjhB, NUDIX family; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.808 |
SHH05195.1 | SHH05171.1 | SAMN04488068_2310 | SAMN04488068_2309 | General secretion pathway protein M; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | General secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | 0.999 |
SHH05195.1 | SHH05215.1 | SAMN04488068_2310 | SAMN04488068_2311 | General secretion pathway protein M; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | Type II secretion system (T2SS), protein N. | 0.826 |
SHH05195.1 | mnmA | SAMN04488068_2310 | SAMN04488068_2313 | General secretion pathway protein M; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | tRNA-specific 2-thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.804 |