STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1049 aa)    
Predicted Functional Partners:
PAN3
PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]
  
 
 0.999
TARUN_8095
Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.
    
 0.972
TARUN_377
Glucose-repressible alcohol dehydrogenase transcriptional effector.
    
 
 0.768
TARUN_6027
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.765
TARUN_6026
Proliferating cell nuclear antigen.
  
 0.765
TARUN_3123
Atp-dependent rna helicase eif4a; Belongs to the DEAD box helicase family.
    
 0.706
TARUN_2327
Atp-dependent rna helicase fal1; Belongs to the DEAD box helicase family.
    
 0.666
TARUN_5302
Dna helicase ii atp-dependent dna helicase.
  
 
 0.643
TARUN_2663
60s ribosomal l7.
   
 0.634
TARUN_10041
Translation initiation factor eif4e; Belongs to the eukaryotic initiation factor 4E family.
     
 0.631
Your Current Organism:
Trichoderma arundinaceum
NCBI taxonomy Id: 490622
Other names: BPI 878405, CBS 119575, T. arundinaceum, Trichoderma arundinaceum Zafari, Graf. & Samuels, 2008, Trichoderma sp. GJS-2007a
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