node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDI33337.1 | SDI81332.1 | SAMN05421850_102232 | SAMN05421850_105262 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.513 |
SDI33337.1 | SDI92206.1 | SAMN05421850_102232 | SAMN05421850_106239 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | 0.666 |
SDI33337.1 | clpB | SAMN05421850_102232 | SAMN05421850_1057 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.765 |
SDI33337.1 | dnaJ | SAMN05421850_102232 | SAMN05421850_105146 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.579 |
SDI33337.1 | dnaK | SAMN05421850_102232 | SAMN05421850_105145 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.663 |
SDI33337.1 | grpE | SAMN05421850_102232 | SAMN05421850_105194 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.594 |
SDI81332.1 | SDI33337.1 | SAMN05421850_105262 | SAMN05421850_102232 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | 0.513 |
SDI81332.1 | SDI89993.1 | SAMN05421850_105262 | SAMN05421850_106166 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Signal transduction histidine kinase. | 0.757 |
SDI81332.1 | SDI92206.1 | SAMN05421850_105262 | SAMN05421850_106239 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | 0.513 |
SDI81332.1 | SDJ06404.1 | SAMN05421850_105262 | SAMN05421850_10831 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Molecular chaperone IbpA, HSP20 family; Belongs to the small heat shock protein (HSP20) family. | 0.513 |
SDI81332.1 | clpB | SAMN05421850_105262 | SAMN05421850_1057 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.784 |
SDI81332.1 | clpP | SAMN05421850_105262 | SAMN05421850_101736 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.559 |
SDI81332.1 | dnaJ | SAMN05421850_105262 | SAMN05421850_105146 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.986 |
SDI81332.1 | dnaK | SAMN05421850_105262 | SAMN05421850_105145 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
SDI81332.1 | grpE | SAMN05421850_105262 | SAMN05421850_105194 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.883 |
SDI89993.1 | SDI81332.1 | SAMN05421850_106166 | SAMN05421850_105262 | Signal transduction histidine kinase. | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.757 |
SDI89993.1 | clpB | SAMN05421850_106166 | SAMN05421850_1057 | Signal transduction histidine kinase. | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.778 |
SDI89993.1 | clpP | SAMN05421850_106166 | SAMN05421850_101736 | Signal transduction histidine kinase. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.461 |
SDI89993.1 | dnaJ | SAMN05421850_106166 | SAMN05421850_105146 | Signal transduction histidine kinase. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.420 |
SDI89993.1 | dnaK | SAMN05421850_106166 | SAMN05421850_105145 | Signal transduction histidine kinase. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.652 |