Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DKAM_0100Ferredoxin:NADP oxidoreductase, alpha subunit. (470 aa)    
Predicted Functional Partners:
DKAM_0099
Ferredoxin:NADP oxidoreductase, beta subunit.
 
 
 0.996
DKAM_0183
Dihydroorotate dehydrogenase family protein.
 
 
 0.952
DKAM_1451
Glu/Leu/Phe/Val dehydrogenase, C terminal; Pfam00208, ELFV_dehydrog, Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.931
DKAM_0468
COG0436 Aspartate/tyrosine/aromatic aminotransferase.
  
 
 0.928
glmS
D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.918
DKAM_1458
Glutamine-fructose-6-phosphate transaminase.
    
 0.918
DKAM_1015
COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
  
  
 
0.915
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.912
DKAM_0524
Amidophosphoribosyltransferase (ATASE).
  
 
 0.912
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
    
 0.902
Your Current Organism:
Desulfurococcus amylolyticus
NCBI taxonomy Id: 490899
Other names: D. amylolyticus 1221n, Desulfurococcus amylolyticus 1221n, Desulfurococcus kamchatkensis 1221n, Proteinoruptor kamchatkensis 1221n
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