STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DKAM_0379Protein of unknown function DUF650; Involved in DNA damage repair; Belongs to the Nre family. (413 aa)    
Predicted Functional Partners:
DKAM_0380
DNA repair photolyase; Radical SAM domain protein.
       0.866
nac
Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
  
     0.644
DKAM_1427
Cell division control protein 6 - like protein, cdc6; Involved in regulation of DNA replication.
  
     0.613
priS
Probable DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer sy [...]
 
     0.598
cdc6
Cell division control protein 6 - like protein, cdc6; Involved in regulation of DNA replication.
  
     0.595
DKAM_0976
Riboflavin kinase.
  
     0.554
DKAM_0936
COG0704 Phosphate uptake regulator.
 
     0.542
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
     0.535
DKAM_0069
Phosphate uptake regulator, PhoU.
 
     0.490
rpl18e
50S ribosomal protein L18e; Belongs to the eukaryotic ribosomal protein eL18 family.
  
     0.489
Your Current Organism:
Desulfurococcus amylolyticus
NCBI taxonomy Id: 490899
Other names: D. amylolyticus 1221n, Desulfurococcus amylolyticus 1221n, Desulfurococcus kamchatkensis 1221n, Proteinoruptor kamchatkensis 1221n
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.