nnrD protein (Desulfurococcus amylolyticus) - STRING interaction network

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nnrD

Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] (517 aa)

Predicted Functional Partners:

DKAM_1033

0.534

DKAM_0955

0.533

DKAM_0477

0.502

DKAM_1261

0.470

DKAM_0190

0.437

DKAM_0483

0.437

DKAM_0525

0.432

DKAM_1450

0.417

pdxS

0.413

DKAM_1107

0.403

Your Current Organism:

Desulfurococcus amylolyticus

NCBI taxonomy Id: 490899
Other names: D. amylolyticus 1221n, Desulfurococcus amylolyticus 1221n, Desulfurococcus kamchatkensis 1221n, Proteinoruptor kamchatkensis 1221n

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DKAM_0190	nnrD	DKAM_0190	DKAM_0484	Putative Na+/H+ antiporter.	Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]	0.437
DKAM_0477	DKAM_0525	DKAM_0477	DKAM_0525	Orotidine-5'-phosphate decarboxylase, PyrF.	Phosphoribosylamine--glycine ligase.	0.501
DKAM_0477	nnrD	DKAM_0477	DKAM_0484	Orotidine-5'-phosphate decarboxylase, PyrF.	Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]	0.502
DKAM_0477	pdxS	DKAM_0477	DKAM_0482	Orotidine-5'-phosphate decarboxylase, PyrF.	Pyridoxal biosynthesis lyase pdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.	0.419
DKAM_0483	nnrD	DKAM_0483	DKAM_0484	Hypothetical protein.	Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]	0.437
DKAM_0483	pdxS	DKAM_0483	DKAM_0482	Hypothetical protein.	Pyridoxal biosynthesis lyase pdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.	0.517
DKAM_0525	DKAM_0477	DKAM_0525	DKAM_0477	Phosphoribosylamine--glycine ligase.	Orotidine-5'-phosphate decarboxylase, PyrF.	0.501
DKAM_0525	nnrD	DKAM_0525	DKAM_0484	Phosphoribosylamine--glycine ligase.	Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]	0.432
DKAM_0955	DKAM_1033	DKAM_0955	DKAM_1033	COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases.	Thermosome subunit alpha; COG0459 Chaperonin GroEL (HSP60 family); Belongs to the TCP-1 chaperonin family.	0.652
DKAM_0955	DKAM_1261	DKAM_0955	DKAM_1261	COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases.	Thermosome subunit beta; COG0459 Chaperonin GroEL (HSP60 family); Belongs to the TCP-1 chaperonin family.	0.652
DKAM_0955	nnrD	DKAM_0955	DKAM_0484	COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases.	Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]	0.533
DKAM_1033	DKAM_0955	DKAM_1033	DKAM_0955	Thermosome subunit alpha; COG0459 Chaperonin GroEL (HSP60 family); Belongs to the TCP-1 chaperonin family.	COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases.	0.652
DKAM_1033	DKAM_1261	DKAM_1033	DKAM_1261	Thermosome subunit alpha; COG0459 Chaperonin GroEL (HSP60 family); Belongs to the TCP-1 chaperonin family.	Thermosome subunit beta; COG0459 Chaperonin GroEL (HSP60 family); Belongs to the TCP-1 chaperonin family.	0.660
DKAM_1033	nnrD	DKAM_1033	DKAM_0484	Thermosome subunit alpha; COG0459 Chaperonin GroEL (HSP60 family); Belongs to the TCP-1 chaperonin family.	Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]	0.534
DKAM_1107	nnrD	DKAM_1107	DKAM_0484	Probable signal recognition particle protein.	Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]	0.403
DKAM_1261	DKAM_0955	DKAM_1261	DKAM_0955	Thermosome subunit beta; COG0459 Chaperonin GroEL (HSP60 family); Belongs to the TCP-1 chaperonin family.	COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases.	0.652
DKAM_1261	DKAM_1033	DKAM_1261	DKAM_1033	Thermosome subunit beta; COG0459 Chaperonin GroEL (HSP60 family); Belongs to the TCP-1 chaperonin family.	Thermosome subunit alpha; COG0459 Chaperonin GroEL (HSP60 family); Belongs to the TCP-1 chaperonin family.	0.660
DKAM_1261	nnrD	DKAM_1261	DKAM_0484	Thermosome subunit beta; COG0459 Chaperonin GroEL (HSP60 family); Belongs to the TCP-1 chaperonin family.	Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]	0.470
DKAM_1450	nnrD	DKAM_1450	DKAM_0484	Isochorismatase hydrolase; COG1335 Amidases related to nicotinamidase; pfam00857, Isochorismatase, Isochorismatase family.	Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]	0.417
nnrD	DKAM_0190	DKAM_0484	DKAM_0190	Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]	Putative Na+/H+ antiporter.	0.437

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