node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DKAM_0020 | DKAM_0433 | DKAM_0020 | DKAM_0433 | TATA binding protein (TBP)-interacting protein (TIP49-like). | Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | 0.527 |
DKAM_0020 | glpK | DKAM_0020 | DKAM_0882 | TATA binding protein (TBP)-interacting protein (TIP49-like). | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | 0.999 |
DKAM_0020 | psmA | DKAM_0020 | DKAM_1327 | TATA binding protein (TBP)-interacting protein (TIP49-like). | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.509 |
DKAM_0020 | psmB1 | DKAM_0020 | DKAM_1278 | TATA binding protein (TBP)-interacting protein (TIP49-like). | Proteasome subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.415 |
DKAM_0433 | DKAM_0020 | DKAM_0433 | DKAM_0020 | Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | TATA binding protein (TBP)-interacting protein (TIP49-like). | 0.527 |
DKAM_0433 | DKAM_0862 | DKAM_0433 | DKAM_0862 | Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.780 |
DKAM_0433 | glpK | DKAM_0433 | DKAM_0882 | Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | 0.907 |
DKAM_0433 | pan | DKAM_0433 | DKAM_1268 | Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.932 |
DKAM_0433 | psmA | DKAM_0433 | DKAM_1327 | Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.670 |
DKAM_0433 | psmB1 | DKAM_0433 | DKAM_1278 | Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | Proteasome subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.670 |
DKAM_0433 | psmB2 | DKAM_0433 | DKAM_1288 | Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | Proteasome subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.670 |
DKAM_0862 | DKAM_0433 | DKAM_0862 | DKAM_0433 | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | 0.780 |
DKAM_0862 | glpK | DKAM_0862 | DKAM_0882 | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | 0.923 |
DKAM_0862 | pan | DKAM_0862 | DKAM_1268 | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.926 |
DKAM_0862 | psmA | DKAM_0862 | DKAM_1327 | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.858 |
DKAM_0862 | psmB1 | DKAM_0862 | DKAM_1278 | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | Proteasome subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.858 |
DKAM_0862 | psmB2 | DKAM_0862 | DKAM_1288 | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | Proteasome subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.858 |
DKAM_0878 | glpK | DKAM_0878 | DKAM_0882 | Glycerophosphoryl diester phosphodiesterase. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | 0.810 |
DKAM_0880 | DKAM_0881 | DKAM_0880 | DKAM_0881 | NADH oxidase. | Glycerol-3-phosphate dehydrogenase; KEGG: FAD dependent oxidoreductase. | 0.993 |
DKAM_0880 | glpK | DKAM_0880 | DKAM_0882 | NADH oxidase. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | 0.887 |