STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcmprotein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. (227 aa)    
Predicted Functional Partners:
DKAM_0955
COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases.
  
   0.708
DKAM_0238
Radical SAM domain protein; COG0731 Fe-S oxidoreductases.
  
    0.580
taw1
Wyosine base formation; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
  
    0.580
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.515
DKAM_0530
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
  
 0.478
eIF5A
Translation initiation factor IF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
     
 0.461
DKAM_1450
Isochorismatase hydrolase; COG1335 Amidases related to nicotinamidase; pfam00857, Isochorismatase, Isochorismatase family.
  
   0.415
DKAM_1075
tRNA pseudouridine synthase D.
     
 0.405
Your Current Organism:
Desulfurococcus amylolyticus
NCBI taxonomy Id: 490899
Other names: D. amylolyticus 1221n, Desulfurococcus amylolyticus 1221n, Desulfurococcus kamchatkensis 1221n, Proteinoruptor kamchatkensis 1221n
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