node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DKAM_0299 | glyA | DKAM_0299 | DKAM_0300 | gcvT; glycine cleavage system aminomethyltransferase T; K00605 aminomethyltransferase. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.998 |
DKAM_0299 | purT | DKAM_0299 | DKAM_0526 | gcvT; glycine cleavage system aminomethyltransferase T; K00605 aminomethyltransferase. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.911 |
DKAM_0299 | thyX | DKAM_0299 | DKAM_1120 | gcvT; glycine cleavage system aminomethyltransferase T; K00605 aminomethyltransferase. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.914 |
DKAM_0955 | eno | DKAM_0955 | DKAM_1440 | COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.490 |
DKAM_0955 | glyA | DKAM_0955 | DKAM_0300 | COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.475 |
DKAM_0955 | pyrG | DKAM_0955 | DKAM_0057 | COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.606 |
DKAM_0955 | thyX | DKAM_0955 | DKAM_1120 | COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.518 |
DKAM_1118 | DKAM_1119 | DKAM_1118 | DKAM_1119 | Anaerobic ribonucleoside triphosphate reductase; Protein product contain self-splicing intein. | Anaerobic ribonucleoside-triphosphate reductase activating protein. | 0.953 |
DKAM_1118 | dcd | DKAM_1118 | DKAM_1136 | Anaerobic ribonucleoside triphosphate reductase; Protein product contain self-splicing intein. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.915 |
DKAM_1118 | pyrG | DKAM_1118 | DKAM_0057 | Anaerobic ribonucleoside triphosphate reductase; Protein product contain self-splicing intein. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.918 |
DKAM_1118 | thyX | DKAM_1118 | DKAM_1120 | Anaerobic ribonucleoside triphosphate reductase; Protein product contain self-splicing intein. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.706 |
DKAM_1119 | DKAM_1118 | DKAM_1119 | DKAM_1118 | Anaerobic ribonucleoside-triphosphate reductase activating protein. | Anaerobic ribonucleoside triphosphate reductase; Protein product contain self-splicing intein. | 0.953 |
DKAM_1119 | thyX | DKAM_1119 | DKAM_1120 | Anaerobic ribonucleoside-triphosphate reductase activating protein. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.842 |
dcd | DKAM_1118 | DKAM_1136 | DKAM_1118 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Anaerobic ribonucleoside triphosphate reductase; Protein product contain self-splicing intein. | 0.915 |
dcd | pyrG | DKAM_1136 | DKAM_0057 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.940 |
dcd | thyX | DKAM_1136 | DKAM_1120 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.507 |
dcd | tmk | DKAM_1136 | DKAM_0141 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Thymidylate kinase. | 0.521 |
eno | DKAM_0955 | DKAM_1440 | DKAM_0955 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases. | 0.490 |
eno | glyA | DKAM_1440 | DKAM_0300 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.490 |
eno | pyrG | DKAM_1440 | DKAM_0057 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.671 |