STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C5L36_0A04160Protein kinase domain-containing protein. (530 aa)    
Predicted Functional Partners:
C5L36_0A13010
Uncharacterized protein.
    
 0.990
C5L36_0C09140
Uncharacterized protein.
    
 
 0.980
C5L36_0B05870
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.937
BOH78_2842
Cyclin pch1; Belongs to the cyclin family.
    
 0.925
C5L36_0C06280
Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.
    
 0.864
C5L36_0A07730
RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.
   
 0.747
C5L36_0B09540
Uncharacterized protein.
   
 0.730
C5L36_0C10150
Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.
    
 0.717
BOH78_1552
Serine/threonine-protein kinase KIN28; Belongs to the protein kinase superfamily.
  
 
0.713
C5L36_0B06580
CYCLIN domain-containing protein; Belongs to the cyclin family.
    
 0.697
Your Current Organism:
Pichia kudriavzevii
NCBI taxonomy Id: 4909
Other names: AJ 4457 [[Candida krusei]], ATCC 24210, ATCC 6258 [[Candida krusei]], ATCC 749 [[Candida krusei]], CBS 5147, CBS 5147 T, CBS 573 [[Candida krusei]], Candida acidothermophilum, Candida krusei, DBVPG 7230 [[Candida krusei]], IAM 12186 [[Candida krusei]], Issatchenkia orientalis, NRRL Y-413 [[Candida krusei]], NRRL Y-5396, NRRL Y-7179 [[Candida krusei]], P. kudriavzevii, Saccharomyces krusei, Saccharomyces sp. p1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.