C5L36_0A04920 protein (Pichia kudriavzevii) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

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Score

C5L36_0A04920

Zn(2)-C6 fungal-type domain-containing protein. (592 aa)

Predicted Functional Partners:

BOH78_1399

0.605

C5L36_0B06920

0.600

C5L36_0D06290

0.581

BOH78_3605

0.418

C5L36_0B10780

0.411

C5L36_0B09885

0.410

C5L36_0D00620

0.410

Your Current Organism:

Pichia kudriavzevii

NCBI taxonomy Id: 4909
Other names: AJ 4457 [[Candida krusei]], ATCC 24210, ATCC 6258 [[Candida krusei]], ATCC 749 [[Candida krusei]], CBS 5147, CBS 5147 T, CBS 573 [[Candida krusei]], Candida acidothermophilum, Candida krusei, DBVPG 7230 [[Candida krusei]], IAM 12186 [[Candida krusei]], Issatchenkia orientalis, NRRL Y-413 [[Candida krusei]], NRRL Y-5396, NRRL Y-7179 [[Candida krusei]], P. kudriavzevii, Saccharomyces krusei, Saccharomyces sp. p1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BOH78_1399	C5L36_0A04920	A0A1V2LR18	A0A2U9QY25	Uncharacterized protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.605
BOH78_3605	C5L36_0A04920	A0A1V2LJA7	A0A2U9QY25	UBX domain-containing protein 1.	Zn(2)-C6 fungal-type domain-containing protein.	0.418
C5L36_0A04920	BOH78_1399	A0A2U9QY25	A0A1V2LR18	Zn(2)-C6 fungal-type domain-containing protein.	Uncharacterized protein.	0.605
C5L36_0A04920	BOH78_3605	A0A2U9QY25	A0A1V2LJA7	Zn(2)-C6 fungal-type domain-containing protein.	UBX domain-containing protein 1.	0.418
C5L36_0A04920	C5L36_0B06920	A0A2U9QY25	A0A099NWJ1	Zn(2)-C6 fungal-type domain-containing protein.	Ubiquitin-40S ribosomal protein S27a.	0.600
C5L36_0A04920	C5L36_0B09885	A0A2U9QY25	A0A1Z8JJT6	Zn(2)-C6 fungal-type domain-containing protein.	Ubiquitin-60S ribosomal protein L40.	0.410
C5L36_0A04920	C5L36_0B10780	A0A2U9QY25	A0A2U9R3C3	Zn(2)-C6 fungal-type domain-containing protein.	GRIP domain-containing protein.	0.411
C5L36_0A04920	C5L36_0D00620	A0A2U9QY25	A0A2U9R7K3	Zn(2)-C6 fungal-type domain-containing protein.	Uncharacterized protein.	0.410
C5L36_0A04920	C5L36_0D06290	A0A2U9QY25	A0A2U9R968	Zn(2)-C6 fungal-type domain-containing protein.	Uncharacterized protein.	0.581
C5L36_0B06920	C5L36_0A04920	A0A099NWJ1	A0A2U9QY25	Ubiquitin-40S ribosomal protein S27a.	Zn(2)-C6 fungal-type domain-containing protein.	0.600
C5L36_0B06920	C5L36_0B09885	A0A099NWJ1	A0A1Z8JJT6	Ubiquitin-40S ribosomal protein S27a.	Ubiquitin-60S ribosomal protein L40.	0.999
C5L36_0B06920	C5L36_0D00620	A0A099NWJ1	A0A2U9R7K3	Ubiquitin-40S ribosomal protein S27a.	Uncharacterized protein.	0.974
C5L36_0B09885	C5L36_0A04920	A0A1Z8JJT6	A0A2U9QY25	Ubiquitin-60S ribosomal protein L40.	Zn(2)-C6 fungal-type domain-containing protein.	0.410
C5L36_0B09885	C5L36_0B06920	A0A1Z8JJT6	A0A099NWJ1	Ubiquitin-60S ribosomal protein L40.	Ubiquitin-40S ribosomal protein S27a.	0.999
C5L36_0B10780	C5L36_0A04920	A0A2U9R3C3	A0A2U9QY25	GRIP domain-containing protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.411
C5L36_0D00620	C5L36_0A04920	A0A2U9R7K3	A0A2U9QY25	Uncharacterized protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.410
C5L36_0D00620	C5L36_0B06920	A0A2U9R7K3	A0A099NWJ1	Uncharacterized protein.	Ubiquitin-40S ribosomal protein S27a.	0.974
C5L36_0D06290	C5L36_0A04920	A0A2U9R968	A0A2U9QY25	Uncharacterized protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.581

Network Stats

number of nodes:

11

number of edges:

24

average node degree:

4.36

avg. local clustering coefficient:

0.856

expected number of edges:

33

PPI enrichment p-value:

0.959

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2713

Alpha/beta hydrolase fold-1

4 of 6

2.57

3.35

1.13e-06

CL:1085

Phosphopantetheine attachment site, and Thioesterase domain

2 of 10

2.04

0.79

0.0417

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031975

Envelope

4 of 85

1.42

1.1

0.0033

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0596

Phosphopantetheine

3 of 47

1.55

0.9

0.0158

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00561

Alpha/beta hydrolase fold

3 of 22

1.88

1.19

0.0061

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000073

Alpha/beta hydrolase fold-1

4 of 22

2.0

2.04

0.00012

IPR032821

Polyketide synthase, C-terminal extension

3 of 16

2.02

1.4

0.0028

IPR013968

Polyketide synthase, ketoreductase domain

3 of 15

2.04

1.4

0.0028

IPR016036

Malonyl-CoA ACP transacylase, ACP-binding

3 of 17

1.99

1.39

0.0028

IPR014043

Acyl transferase

3 of 17

1.99

1.39

0.0028

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00822

This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group.

3 of 13

2.11

1.88

0.00034

SM00827

Acyl transferase domain in polyketide synthase (PKS) enzymes.

3 of 15

2.04

1.85

0.00034

SM00823

Phosphopantetheine attachment site

3 of 16

2.02

1.84

0.00034

SM00826

PKS_DH

2 of 4

2.44

1.61

0.0016

SM00825

Beta-ketoacyl synthase

2 of 12

1.96

1.16

0.0078

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