STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C5L36_0B02180Uncharacterized protein. (1172 aa)    
Predicted Functional Partners:
C5L36_0D04470
B30.2/SPRY domain-containing protein.
    
 0.750
C5L36_0C06810
Uncharacterized protein.
    
 0.747
BOH78_1604
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.712
BOH78_0841
Histone H2B; Belongs to the histone H2B family.
   
  0.654
C5L36_0A03460
Uncharacterized protein.
   
 0.575
MED20
Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
 0.519
BOH78_2101
Histone H3-like centromeric protein CSE4.
    
 0.504
BOH78_4780
Uncharacterized protein.
    
 0.504
BOH78_1603
Histone H3; Belongs to the histone H3 family.
    
 0.504
C5L36_0B12080
Fe2OG dioxygenase domain-containing protein.
    
 0.504
Your Current Organism:
Pichia kudriavzevii
NCBI taxonomy Id: 4909
Other names: AJ 4457 [[Candida krusei]], ATCC 24210, ATCC 6258 [[Candida krusei]], ATCC 749 [[Candida krusei]], CBS 5147, CBS 5147 T, CBS 573 [[Candida krusei]], Candida acidothermophilum, Candida krusei, DBVPG 7230 [[Candida krusei]], IAM 12186 [[Candida krusei]], Issatchenkia orientalis, NRRL Y-413 [[Candida krusei]], NRRL Y-5396, NRRL Y-7179 [[Candida krusei]], P. kudriavzevii, Saccharomyces krusei, Saccharomyces sp. p1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.