STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C5L36_0C02050Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (555 aa)    
Predicted Functional Partners:
BOH78_3644
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.
  
 
 0.999
BOH78_4173
Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family.
 
 0.999
C5L36_0B02160
Histidine biosynthesis trifunctional protein.
 
 0.999
BOH78_3766
ATP phosphoribosyltransferase.
 
 
 0.996
BOH78_4607
Histidinol-phosphate aminotransferase.
 
 
 0.995
BOH78_3782
Bifunctional purine biosynthesis protein ADE17.
  
 
 0.968
C5L36_0A07180
DNA 3'-phosphatase.
  
 
 0.945
C5L36_0B02170
Uncharacterized protein.
  
 
 0.929
BOH78_2637
Phosphoserine phosphatase.
  
  
 0.912
BOH78_2178
Tryptophan synthase.
  
  
 0.893
Your Current Organism:
Pichia kudriavzevii
NCBI taxonomy Id: 4909
Other names: AJ 4457 [[Candida krusei]], ATCC 24210, ATCC 6258 [[Candida krusei]], ATCC 749 [[Candida krusei]], CBS 5147, CBS 5147 T, CBS 573 [[Candida krusei]], Candida acidothermophilum, Candida krusei, DBVPG 7230 [[Candida krusei]], IAM 12186 [[Candida krusei]], Issatchenkia orientalis, NRRL Y-413 [[Candida krusei]], NRRL Y-5396, NRRL Y-7179 [[Candida krusei]], P. kudriavzevii, Saccharomyces krusei, Saccharomyces sp. p1
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