STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msbAATP-binding cassette, subfamily B, MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (598 aa)    
Predicted Functional Partners:
lpxK
lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
  
 0.957
SIP92699.1
Amino acid ABC transporter ATP-binding protein, PAAT family.
 
    
0.904
SIQ74342.1
Amino acid ABC transporter ATP-binding protein, PAAT family.
 
     
0.900
SIP99649.1
ATP-binding cassette, subfamily C, LapB.
 
 
0.896
SIQ27262.1
ATP-binding cassette, subfamily C, LapB.
 
 
0.896
SIQ47673.1
3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
   
 0.874
lolD
Lipoprotein-releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.
   
0.761
SIQ47631.1
UDPglucose 6-dehydrogenase.
     
 0.675
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.650
SIQ28188.1
Protein tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
   
 
 0.648
Your Current Organism:
Marinobacterium stanieri
NCBI taxonomy Id: 49186
Other names: ATCC 27130, CCUG 16021, CIP 106697, DSM 7027, LMG 6847, LMG:6847, M. stanieri, Pseudomonas stanieri, strain 146
Server load: low (18%) [HD]