STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
miaB2-methylthioadenine synthetase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (527 aa)    
Predicted Functional Partners:
Aflv_1522
Uncharacterized conserved protein; Belongs to the UPF0342 family.
  
    0.815
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
  
 0.796
cotE
Outer spore coat protein.
 
     0.656
Aflv_1789
rRNA cytosine-C5-methylase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.645
Aflv_1524
2-oxoglutarate ferredoxin oxidoreductase, beta subunit.
 
    0.640
Aflv_1525
2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
       0.618
rlmN
Predicted Fe-S-cluster redox enzyme; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
 
  
 0.618
mrp
Mrp protein, an ATPase involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
  
   
 0.567
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
    
   0.545
Aflv_0303
Multidomain redox protein (NAD(FAD)-dependent oxidoreductase; Rhodanese domain; SirA-like redox domain; Peroxiredoxin domain); Belongs to the sulfur carrier protein TusA family.
  
 
 0.494
Your Current Organism:
Anoxybacillus flavithermus
NCBI taxonomy Id: 491915
Other names: A. flavithermus WK1, Anoxybacillus flavithermus WK1, Anoxybacillus flavithermus str. WK1, Anoxybacillus flavithermus strain WK1
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