node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEF53114.1 | AEF54317.1 | Mar181_0045 | Mar181_1270 | TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: hch:HCH_00873 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. | TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: pag:PLES_37401 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. | 0.909 |
AEF53114.1 | AEF54348.1 | Mar181_0045 | Mar181_1301 | TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: hch:HCH_00873 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. | KEGG: pmy:Pmen_4129 sarcosine oxidase alpha subunit family protein; TIGRFAM: Sarcosine oxidase, alpha subunit, heterotetrameric; PFAM: Glycine cleavage T-protein, N-terminal; HI0933-like protein; Glycine cleavage T-protein, C-terminal barrel; Belongs to the GcvT family. | 0.472 |
AEF53114.1 | AEF54721.1 | Mar181_0045 | Mar181_1683 | TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: hch:HCH_00873 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. | TIGRFAM: Glycine cleavage system T protein; KEGG: vsa:VSAL_II0496 glycine cleavage system T protein; PFAM: Glycine cleavage T-protein, N-terminal; Glycine cleavage T-protein, C-terminal barrel. | 0.930 |
AEF53114.1 | AEF55536.1 | Mar181_0045 | Mar181_2503 | TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: hch:HCH_00873 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. | PFAM: Glycine cleavage T-protein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Glycine cleavage T-protein, C-terminal barrel; KEGG: pfs:PFLU2317 putative sarcosine oxidase subunit alpha; Belongs to the GcvT family. | 0.489 |
AEF53114.1 | gcvH | Mar181_0045 | Mar181_1681 | TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: hch:HCH_00873 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.961 |
AEF53114.1 | gcvP | Mar181_0045 | Mar181_1680 | TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: hch:HCH_00873 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.950 |
AEF53114.1 | glyA | Mar181_0045 | Mar181_1682 | TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: hch:HCH_00873 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.911 |
AEF54317.1 | AEF53114.1 | Mar181_1270 | Mar181_0045 | TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: pag:PLES_37401 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. | TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: hch:HCH_00873 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. | 0.909 |
AEF54317.1 | AEF54348.1 | Mar181_1270 | Mar181_1301 | TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: pag:PLES_37401 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. | KEGG: pmy:Pmen_4129 sarcosine oxidase alpha subunit family protein; TIGRFAM: Sarcosine oxidase, alpha subunit, heterotetrameric; PFAM: Glycine cleavage T-protein, N-terminal; HI0933-like protein; Glycine cleavage T-protein, C-terminal barrel; Belongs to the GcvT family. | 0.472 |
AEF54317.1 | AEF54721.1 | Mar181_1270 | Mar181_1683 | TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: pag:PLES_37401 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. | TIGRFAM: Glycine cleavage system T protein; KEGG: vsa:VSAL_II0496 glycine cleavage system T protein; PFAM: Glycine cleavage T-protein, N-terminal; Glycine cleavage T-protein, C-terminal barrel. | 0.935 |
AEF54317.1 | AEF55536.1 | Mar181_1270 | Mar181_2503 | TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: pag:PLES_37401 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. | PFAM: Glycine cleavage T-protein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Glycine cleavage T-protein, C-terminal barrel; KEGG: pfs:PFLU2317 putative sarcosine oxidase subunit alpha; Belongs to the GcvT family. | 0.489 |
AEF54317.1 | gcvH | Mar181_1270 | Mar181_1681 | TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: pag:PLES_37401 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.965 |
AEF54317.1 | gcvP | Mar181_1270 | Mar181_1680 | TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: pag:PLES_37401 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.950 |
AEF54317.1 | glyA | Mar181_1270 | Mar181_1682 | TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: pag:PLES_37401 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.911 |
AEF54348.1 | AEF53114.1 | Mar181_1301 | Mar181_0045 | KEGG: pmy:Pmen_4129 sarcosine oxidase alpha subunit family protein; TIGRFAM: Sarcosine oxidase, alpha subunit, heterotetrameric; PFAM: Glycine cleavage T-protein, N-terminal; HI0933-like protein; Glycine cleavage T-protein, C-terminal barrel; Belongs to the GcvT family. | TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: hch:HCH_00873 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. | 0.472 |
AEF54348.1 | AEF54317.1 | Mar181_1301 | Mar181_1270 | KEGG: pmy:Pmen_4129 sarcosine oxidase alpha subunit family protein; TIGRFAM: Sarcosine oxidase, alpha subunit, heterotetrameric; PFAM: Glycine cleavage T-protein, N-terminal; HI0933-like protein; Glycine cleavage T-protein, C-terminal barrel; Belongs to the GcvT family. | TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: pag:PLES_37401 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. | 0.472 |
AEF54348.1 | AEF55536.1 | Mar181_1301 | Mar181_2503 | KEGG: pmy:Pmen_4129 sarcosine oxidase alpha subunit family protein; TIGRFAM: Sarcosine oxidase, alpha subunit, heterotetrameric; PFAM: Glycine cleavage T-protein, N-terminal; HI0933-like protein; Glycine cleavage T-protein, C-terminal barrel; Belongs to the GcvT family. | PFAM: Glycine cleavage T-protein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Glycine cleavage T-protein, C-terminal barrel; KEGG: pfs:PFLU2317 putative sarcosine oxidase subunit alpha; Belongs to the GcvT family. | 0.957 |
AEF54348.1 | gcvH | Mar181_1301 | Mar181_1681 | KEGG: pmy:Pmen_4129 sarcosine oxidase alpha subunit family protein; TIGRFAM: Sarcosine oxidase, alpha subunit, heterotetrameric; PFAM: Glycine cleavage T-protein, N-terminal; HI0933-like protein; Glycine cleavage T-protein, C-terminal barrel; Belongs to the GcvT family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.942 |
AEF54348.1 | gcvP | Mar181_1301 | Mar181_1680 | KEGG: pmy:Pmen_4129 sarcosine oxidase alpha subunit family protein; TIGRFAM: Sarcosine oxidase, alpha subunit, heterotetrameric; PFAM: Glycine cleavage T-protein, N-terminal; HI0933-like protein; Glycine cleavage T-protein, C-terminal barrel; Belongs to the GcvT family. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
AEF54348.1 | glyA | Mar181_1301 | Mar181_1682 | KEGG: pmy:Pmen_4129 sarcosine oxidase alpha subunit family protein; TIGRFAM: Sarcosine oxidase, alpha subunit, heterotetrameric; PFAM: Glycine cleavage T-protein, N-terminal; HI0933-like protein; Glycine cleavage T-protein, C-terminal barrel; Belongs to the GcvT family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.976 |