STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NCP1NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (675 aa)    
Predicted Functional Partners:
ECM17.1
Sulfite reductase [NADPH] beta subunit (Extracellular matrix protein 17).
0.794
ECM17.2
Sulfite reductase [NADPH] beta subunit (Extracellular matrix protein 17).
  
 0.758
SAM4
AdoMet-homocysteine methyltransferase.
  
 0.710
KAR2
DnaK/HSP70/ BiP family ATPase and chaperone; Belongs to the heat shock protein 70 family.
    
 
 0.702
CP51
Sterol 14alpha-demethylase; Belongs to the cytochrome P450 family.
   
 
 0.698
KAP1
Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate.
  
  
 0.688
HMX1
Heme binding protein.
    
 
 0.679
CYB5
Cytochrome b5; Belongs to the cytochrome b5 family.
   
 
 0.667
PICST_49723
Phosphoadenosine phosphosulfate reductase.
  
 
 0.667
DRE2
Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...]
    
 0.641
Your Current Organism:
Scheffersomyces stipitis
NCBI taxonomy Id: 322104
Other names: Pichia stipitis CBS 6054, S. stipitis CBS 6054, Scheffersomyces stipitis CBS 6054
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