Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mtrTryptophan transporter of high affinity; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)    
Predicted Functional Partners:
apaH_2
Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
    
   0.729
putA
Bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
 
   
 0.548
mtrE_4
Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.467
yccS
TIGR01666 family membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.423
acrR
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.403
acrA
Efflux transporter periplasmic adaptor subunit; MexX; AmrA; involved in resistance to antibiotics; periplasmic membrane fusion protein; functions along with MexY and OprM; part of an inducible system that appears to respond to interference with the cellular translation machinery; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.402
BWD07_11600
2OG-Fe(II) oxygenase; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.400
Your Current Organism:
Neisseria canis
NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6
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