STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speE_1Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (504 aa)    
Predicted Functional Partners:
speH
Adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
 
  
  0.987
speE_2
Catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.933
mtnN
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
     
 0.926
OSI12108.1
Twin-arginine translocation pathway signal; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.843
OSI12003.1
Twin-arginine translocation pathway signal; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.836
OSI13500.1
DUF4178 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.796
OSI13501.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.746
yjfL
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.520
OSI13128.1
5'-methylthioadenosine phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.428
Your Current Organism:
Neisseria canis
NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.