Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
qseCHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)    
Predicted Functional Partners:
rssB
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.978
lpdA
Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.948
ompR
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.908
OSI06652.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.892
baeS
Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
0.882
rbsB
D-ribose ABC transporter substrate-binding protein RbsB; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.815
OSI13204.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.708
macB
Macrolide ABC transporter permease/ATP-binding protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
   
 
 0.648
msrAB
Trifunctional thioredoxin/methionine sulfoxide reductase A/B protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.592
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
    
 0.591
Your Current Organism:
Neisseria canis
NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6
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