Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
macAEfflux transporter periplasmic adaptor subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (395 aa)    
Predicted Functional Partners:
macB
Macrolide ABC transporter permease/ATP-binding protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.997
acrB
Multidrug efflux RND transporter permease subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.941
mtrE_3
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.915
OSI12643.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.816
natC
Hypothetical protein; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.791
OSI13340.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.738
mtrE_4
Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.692
mtrE_2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.624
mtrE_1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.601
OSI12749.1
Acriflavin resistance protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.511
Your Current Organism:
Neisseria canis
NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6
Server load: low (38%) [HD]