Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ubiXAromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (205 aa)    
Predicted Functional Partners:
ubiD
3-octaprenyl-4-hydroxybenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
 
 
 0.992
ubiA
4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
 
  
 0.958
nudF
ADP-ribose pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
nfrA1
NADPH-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the flavin oxidoreductase frp family.
     
  0.900
hpaC
4-hydroxyphenylacetate 3-monooxygenase, reductase component; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.900
frp
Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the flavin oxidoreductase frp family.
     
  0.900
ubiF
Ubiquinone biosynthesis protein UbiH; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.900
OSI13321.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.636
sdcS
Anion:sodium symporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.423
OSI13259.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.400
Your Current Organism:
Neisseria canis
NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6
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