close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OSI13065.1Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa)    
Predicted Functional Partners:
OSI10802.1
Nickel-dependent hydrogenase b-type cytochrome subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.724
OSI13383.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.560
ydfG
NADP-dependent 3-hydroxy acid dehydrogenase; NADP(+)-dependent; catalyzes the formation of 3-hydroxypropionate from the toxic malonic semialdehyde, catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.550
OSI13064.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.547
OSI12720.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.495
dsbB
Disulfide bond formation protein B; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.489
dipZ
Protein-disulfide reductase DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
      
 0.477
zur
Cation uptake regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family.
 
     0.474
OSI13384.1
GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.466
OSI12886.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.409
Your Current Organism:
Neisseria canis
NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.