Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
golBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (248 aa)    
Predicted Functional Partners:
gloA
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
 
 0.983
OSI13399.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
0.910
dld
D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.
     
  0.900
nudF
ADP-ribose pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.780
radC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0758 family.
       0.558
mraZ
Division/cell wall cluster transcriptional repressor MraZ; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MraZ family.
      
 0.514
dgt
Deoxyguanosinetriphosphate triphosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.499
OSI13043.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.481
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
      
 0.480
grxD
Monothiol glutaredoxin, Grx4 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaredoxin family. Monothiol subfamily.
  
   
 0.478
Your Current Organism:
Neisseria canis
NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6
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