| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OSI12731.1 | OSI12733.1 | BWD07_03550 | BWD07_03560 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.752 |
| OSI12731.1 | proC | BWD07_03550 | BWD07_03555 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.654 |
| OSI12733.1 | OSI12731.1 | BWD07_03560 | BWD07_03550 | YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.752 |
| OSI12733.1 | hemN_2 | BWD07_03560 | BWD07_02935 | YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.533 |
| OSI12733.1 | mtnN | BWD07_03560 | BWD07_03110 | YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.617 |
| OSI12733.1 | murF | BWD07_03560 | BWD07_09540 | YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.532 |
| OSI12733.1 | pilT_1 | BWD07_03560 | BWD07_03565 | YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.600 |
| OSI12733.1 | pilT_2 | BWD07_03560 | BWD07_03570 | YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Type IV pili twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.555 |
| OSI12733.1 | proC | BWD07_03560 | BWD07_03555 | YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.749 |
| OSI12733.1 | topA | BWD07_03560 | BWD07_11150 | YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.509 |
| OSI12733.1 | yfiH | BWD07_03560 | BWD07_06460 | YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Multi-copper polyphenol oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.691 |
| OSI12733.1 | yhdE | BWD07_03560 | BWD07_08895 | YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Septum formation inhibitor Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.745 |
| hemN_2 | OSI12733.1 | BWD07_02935 | BWD07_03560 | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.533 |
| mtnN | OSI12733.1 | BWD07_03110 | BWD07_03560 | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.617 |
| murF | OSI12733.1 | BWD07_09540 | BWD07_03560 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.532 |
| pilT_1 | OSI12733.1 | BWD07_03565 | BWD07_03560 | Twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology. | YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.600 |
| pilT_1 | pilT_2 | BWD07_03565 | BWD07_03570 | Twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type IV pili twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.801 |
| pilT_1 | proC | BWD07_03565 | BWD07_03555 | Twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.490 |
| pilT_2 | OSI12733.1 | BWD07_03570 | BWD07_03560 | Type IV pili twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology. | YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.555 |
| pilT_2 | pilT_1 | BWD07_03570 | BWD07_03565 | Type IV pili twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology. | Twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.801 |
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