Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
OSI12476.1Recombinase RecA; Derived by automated computational analysis using gene prediction method: Protein Homology. (84 aa)    
Predicted Functional Partners:
OSI10164.1
Patatin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.738
nifU
Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
       0.631
iscA
Iron-sulfur cluster assembly protein IscA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family.
       0.608
OSI12303.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.529
OSI12478.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.516
OSI11665.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.512
OSI12302.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.507
OSI12765.1
CAAX protease family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.487
OSI12039.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.467
iscS
IscS subfamily cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
       0.411
Your Current Organism:
Neisseria canis
NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6
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