| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OSI12028.1 | corA | BWD07_07370 | BWD07_07375 | acyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Magnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family. | 0.605 |
| OSI12028.1 | ribE | BWD07_07370 | BWD07_07365 | acyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Riboflavin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.567 |
| corA | OSI12028.1 | BWD07_07375 | BWD07_07370 | Magnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family. | acyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.605 |
| corA | ribE | BWD07_07375 | BWD07_07365 | Magnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family. | Riboflavin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.450 |
| hisC | ribE | BWD07_07835 | BWD07_07365 | Histidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Riboflavin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.559 |
| hpaC | ribB | BWD07_06125 | BWD07_04110 | 4-hydroxyphenylacetate 3-monooxygenase, reductase component; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.522 |
| hpaC | ribE | BWD07_06125 | BWD07_07365 | 4-hydroxyphenylacetate 3-monooxygenase, reductase component; Derived by automated computational analysis using gene prediction method: Protein Homology. | Riboflavin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| hpaC | ribF | BWD07_06125 | BWD07_08930 | 4-hydroxyphenylacetate 3-monooxygenase, reductase component; Derived by automated computational analysis using gene prediction method: Protein Homology. | Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. | 0.901 |
| ribA | ribB | BWD07_05745 | BWD07_04110 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.997 |
| ribA | ribD | BWD07_05745 | BWD07_01565 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.998 |
| ribA | ribE | BWD07_05745 | BWD07_07365 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | Riboflavin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.989 |
| ribA | ribH | BWD07_05745 | BWD07_01775 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.961 |
| ribB | hpaC | BWD07_04110 | BWD07_06125 | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 4-hydroxyphenylacetate 3-monooxygenase, reductase component; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.522 |
| ribB | ribA | BWD07_04110 | BWD07_05745 | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.997 |
| ribB | ribD | BWD07_04110 | BWD07_01565 | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
| ribB | ribE | BWD07_04110 | BWD07_07365 | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | Riboflavin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| ribB | ribF | BWD07_04110 | BWD07_08930 | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. | 0.614 |
| ribB | ribH | BWD07_04110 | BWD07_01775 | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
| ribD | ribA | BWD07_01565 | BWD07_05745 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.998 |
| ribD | ribB | BWD07_01565 | BWD07_04110 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.999 |
