Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
pepNDerived by automated computational analysis using gene prediction method: Protein Homology. (873 aa)    
Predicted Functional Partners:
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 0.938
gshB
Glutathione synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family.
    
 0.909
OSI11800.1
Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.906
ggt
Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.867
aspC
Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.845
cysK
Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
   
 0.825
ygeA
Aspartate/glutamate racemase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/glutamate racemases family.
     
  0.800
lpdA
Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.518
comA
DNA internalization-related competence protein ComEC/Rec2; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.508
Your Current Organism:
Neisseria canis
NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6
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