close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpuB_1TonB-dependent receptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (735 aa)    
Predicted Functional Partners:
OSI12110.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.758
hmuT
ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.743
hemS
Hemin-degrading factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.694
OSI13262.1
DUF3108 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.604
cya_2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.604
OSI11719.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
   0.604
algE7
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.604
hpuB_2
Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
0.556
rebM
SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.556
yfhA
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 0.547
Your Current Organism:
Neisseria canis
NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6
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