Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hemSHemin-degrading factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)    
Predicted Functional Partners:
hmuT
ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.981
hmuV
Ferrichrome ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.880
hpuB_1
TonB-dependent receptor; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.694
yfhA
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 0.687
rebM
SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.619
hpuB_2
Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.411
Your Current Organism:
Neisseria canis
NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6
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