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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
luxALuciferase family oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)    
Predicted Functional Partners:
ascD
CDP-6-deoxy-delta-3,4-glucoseen reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.809
cmpC
ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.747
azr
NADPH-dependent FMN reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.737
cmpB
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.650
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.522
asnO
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.487
OSI12750.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.475
hpaC
4-hydroxyphenylacetate 3-monooxygenase, reductase component; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.475
cysI
Sulfite reductase subunit beta; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
     
 0.459
pta
Phosphate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.446
Your Current Organism:
Neisseria canis
NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6
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