Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dmpI2-hydroxymuconate tautomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 4-oxalocrotonate tautomerase family. (63 aa)    
Predicted Functional Partners:
xylE
Catechol 2,3-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.984
xylJ_2
2-oxo-3-hexenedioate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.977
aldA_2
2-hydroxymuconic semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
 
  
  0.934
hcr
Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.854
bphJ
Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
   
 0.800
OSI11066.1
Phenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.786
bphI
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
   
 0.765
tmoA
Phenol 2-monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.713
mphL
Phenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.699
dmpM
Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.679
Your Current Organism:
Neisseria canis
NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6
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