STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smgHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Smg family. (151 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
   
 0.837
smf
DNA protecting protein DprA; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.780
OSI09908.1
Peptidoglycan-binding protein LysM; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.659
OSI12923.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.649
hemD
Hypothetical protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
     0.644
zapA
Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
  
     0.639
OSI12835.1
DUF3460 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.638
OSI12905.1
Cryptic protein cnp1; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.626
OSI09904.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.618
OSI10825.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.617
Your Current Organism:
Neisseria canis
NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.