node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DAN4 | TDA8 | YJR151C | YAL064C-A | Cell wall mannoprotein; has similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth; Belongs to the SRP1/TIP1 family. | Topoisomerase I damage affected protein 8; Putative protein of unknown function; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene. | 0.612 |
DAN4 | YAL064W-B | YJR151C | YAL064W-B | Cell wall mannoprotein; has similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth; Belongs to the SRP1/TIP1 family. | Uncharacterized membrane protein YAL064W-B; Fungal-specific protein of unknown function. | 0.534 |
FRK1 | YAL064W-B | YPL141C | YAL064W-B | Fatty acyl-CoA synthetase and RNA processing-associated kinase 1; Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication. | Uncharacterized membrane protein YAL064W-B; Fungal-specific protein of unknown function. | 0.539 |
ISF1 | PRM7 | YMR081C | YDL039C | Increasing suppression factor 1; Serine-rich, hydrophilic protein; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants; expression is under glucose control; cotranscribed with NAM7 in a cyp1 mutant; ISF1 has a paralog, MBR1, that arose from the whole genome duplication; Belongs to the ISF1/MBR1 family. | Pheromone-regulated protein; predicted to have one transmembrane segment; promoter contains Gcn4p binding elements; in W303 strain one continuous open reading frame comprising of YDL037C, the intergenic region and YDL039C encodes the IMI1. | 0.446 |
ISF1 | YAL064W-B | YMR081C | YAL064W-B | Increasing suppression factor 1; Serine-rich, hydrophilic protein; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants; expression is under glucose control; cotranscribed with NAM7 in a cyp1 mutant; ISF1 has a paralog, MBR1, that arose from the whole genome duplication; Belongs to the ISF1/MBR1 family. | Uncharacterized membrane protein YAL064W-B; Fungal-specific protein of unknown function. | 0.545 |
ISF1 | YHR213W | YMR081C | YHR213W | Increasing suppression factor 1; Serine-rich, hydrophilic protein; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants; expression is under glucose control; cotranscribed with NAM7 in a cyp1 mutant; ISF1 has a paralog, MBR1, that arose from the whole genome duplication; Belongs to the ISF1/MBR1 family. | Putative uncharacterized protein YAR062W; Pseudogenic fragment with similarity to flocculins; YHR213W has a paralog, YAR062W, that arose from a segmental duplication; Belongs to the flocculin family. | 0.487 |
ISF1 | YHR213W-A | YMR081C | YHR213W-A | Increasing suppression factor 1; Serine-rich, hydrophilic protein; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants; expression is under glucose control; cotranscribed with NAM7 in a cyp1 mutant; ISF1 has a paralog, MBR1, that arose from the whole genome duplication; Belongs to the ISF1/MBR1 family. | Uncharacterized protein YHR213W-A; Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching. | 0.553 |
ISF1 | YMR317W | YMR081C | YMR317W | Increasing suppression factor 1; Serine-rich, hydrophilic protein; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants; expression is under glucose control; cotranscribed with NAM7 in a cyp1 mutant; ISF1 has a paralog, MBR1, that arose from the whole genome duplication; Belongs to the ISF1/MBR1 family. | Uncharacterized protein YMR317W; Putative protein of unknown function; has some similarity to sialidase from Trypanosoma; YMR317W is not an essential gene. | 0.514 |
MAK32 | SNO2 | YCR019W | YNL334C | Protein necessary for stability of L-A dsRNA-containing particles. | Probable pyridoxal 5'-phosphate synthase subunit SNO2; Protein of unknown function; nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin; Belongs to the glutaminase PdxT/SNO family. | 0.515 |
MAK32 | TDA8 | YCR019W | YAL064C-A | Protein necessary for stability of L-A dsRNA-containing particles. | Topoisomerase I damage affected protein 8; Putative protein of unknown function; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene. | 0.832 |
MAK32 | YAL064W-B | YCR019W | YAL064W-B | Protein necessary for stability of L-A dsRNA-containing particles. | Uncharacterized membrane protein YAL064W-B; Fungal-specific protein of unknown function. | 0.697 |
PRM7 | ISF1 | YDL039C | YMR081C | Pheromone-regulated protein; predicted to have one transmembrane segment; promoter contains Gcn4p binding elements; in W303 strain one continuous open reading frame comprising of YDL037C, the intergenic region and YDL039C encodes the IMI1. | Increasing suppression factor 1; Serine-rich, hydrophilic protein; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants; expression is under glucose control; cotranscribed with NAM7 in a cyp1 mutant; ISF1 has a paralog, MBR1, that arose from the whole genome duplication; Belongs to the ISF1/MBR1 family. | 0.446 |
PRM7 | YAL064W-B | YDL039C | YAL064W-B | Pheromone-regulated protein; predicted to have one transmembrane segment; promoter contains Gcn4p binding elements; in W303 strain one continuous open reading frame comprising of YDL037C, the intergenic region and YDL039C encodes the IMI1. | Uncharacterized membrane protein YAL064W-B; Fungal-specific protein of unknown function. | 0.560 |
PRM7 | YHR213W | YDL039C | YHR213W | Pheromone-regulated protein; predicted to have one transmembrane segment; promoter contains Gcn4p binding elements; in W303 strain one continuous open reading frame comprising of YDL037C, the intergenic region and YDL039C encodes the IMI1. | Putative uncharacterized protein YAR062W; Pseudogenic fragment with similarity to flocculins; YHR213W has a paralog, YAR062W, that arose from a segmental duplication; Belongs to the flocculin family. | 0.533 |
PRM7 | YHR213W-A | YDL039C | YHR213W-A | Pheromone-regulated protein; predicted to have one transmembrane segment; promoter contains Gcn4p binding elements; in W303 strain one continuous open reading frame comprising of YDL037C, the intergenic region and YDL039C encodes the IMI1. | Uncharacterized protein YHR213W-A; Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching. | 0.600 |
PRM7 | YMR317W | YDL039C | YMR317W | Pheromone-regulated protein; predicted to have one transmembrane segment; promoter contains Gcn4p binding elements; in W303 strain one continuous open reading frame comprising of YDL037C, the intergenic region and YDL039C encodes the IMI1. | Uncharacterized protein YMR317W; Putative protein of unknown function; has some similarity to sialidase from Trypanosoma; YMR317W is not an essential gene. | 0.796 |
SNO2 | MAK32 | YNL334C | YCR019W | Probable pyridoxal 5'-phosphate synthase subunit SNO2; Protein of unknown function; nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin; Belongs to the glutaminase PdxT/SNO family. | Protein necessary for stability of L-A dsRNA-containing particles. | 0.515 |
SNO2 | TDA8 | YNL334C | YAL064C-A | Probable pyridoxal 5'-phosphate synthase subunit SNO2; Protein of unknown function; nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin; Belongs to the glutaminase PdxT/SNO family. | Topoisomerase I damage affected protein 8; Putative protein of unknown function; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene. | 0.698 |
SNO2 | YAL064W-B | YNL334C | YAL064W-B | Probable pyridoxal 5'-phosphate synthase subunit SNO2; Protein of unknown function; nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin; Belongs to the glutaminase PdxT/SNO family. | Uncharacterized membrane protein YAL064W-B; Fungal-specific protein of unknown function. | 0.605 |
TDA8 | DAN4 | YAL064C-A | YJR151C | Topoisomerase I damage affected protein 8; Putative protein of unknown function; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene. | Cell wall mannoprotein; has similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth; Belongs to the SRP1/TIP1 family. | 0.612 |