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PHO11 protein (Saccharomyces cerevisiae) - STRING interaction network
"PHO11" - One of three repressible acid phosphatases, a glycoprotein that is transported to the cell surface by the secretory pathway in Saccharomyces cerevisiae
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PHO11One of three repressible acid phosphatases, a glycoprotein that is transported to the cell surface by the secretory pathway; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2 (467 aa)    
Predicted Functional Partners:
PHO5
Repressible acid phosphatase (1 of 3) that also mediates extracellular nucleotide-derived phosphate hydrolysis; secretory pathway derived cell surface glycoprotein; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2; Partially mediates extracellular nucleotide derived phosphate hydrolysis along with NPP1 and NPP2 (467 aa)
     
 
0.979
VTC3
Subunit of the vacuolar transporter chaperone (VTC) complex involved in membrane trafficking, vacuolar polyphosphate accumulation, microautophagy and non-autophagic vacuolar fusion; Component of the vacuolar transporter chaperone (VTC) complex, which plays a role in vacuolar membrane fusion. Required for LMA1 release prior to membrane fusion (835 aa)
     
   
  0.968
SPL2
Protein with similarity to cyclin-dependent kinase inhibitors; downregulates low-affinity phosphate transport during phosphate limitation; overproduction suppresses a plc1 null mutation; GFP-fusion protein localizes to the cytoplasm; Putative cyclin-dependent kinase (CDK) inhibitor necessary and sufficient for PHO pathway-dependent down-regulation of low-affinity phosphate transport (148 aa)
     
   
  0.957
PHO84
High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p; High-affinity transporter for external inorganic phosphate. Is not an essential protein, since a constitutive, low affinity pI transporter exists in yeast (587 aa)
     
   
  0.948
PHO12
One of three repressible acid phosphatases, a glycoprotein that is transported to the cell surface by the secretory pathway; nearly identical to Pho11p; upregulated by phosphate starvation (467 aa)
     
   
0.912
THI80
Thiamine pyrophosphokinase, phosphorylates thiamine to produce the coenzyme thiamine pyrophosphate (thiamine diphosphate); Essential protein, it is the only enzyme in yeast capable of synthesizing thiamine pyrophosphate (TPP) (319 aa)
         
  0.904
VTC4
Vacuolar membrane polyphosphate polymerase; subunit of the vacuolar transporter chaperone (VTC) complex involved in synthesis and transfer of polyP to the vacuole; regulates membrane trafficking; role in non-autophagic vacuolar fusion; Component of the vacuolar transporter chaperone (VTC) complex, which plays a role in vacuolar membrane fusion. Required for SEC18/NSF activity in SNARE priming, membrane binding of LMA1 and V(0) trans-complex formation (721 aa)
     
   
  0.902
THI6
Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase; required for thiamine biosynthesis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern; Essential for thiamine biosynthesis. The kinase activity is involved in the salvage synthesis of TH-P from the thiazole (540 aa)
         
    0.900
PHM6
Protein of unknown function, expression is regulated by phosphate levels (104 aa)
     
   
  0.895
PHO89
Na+/Pi cotransporter, active in early growth phase; similar to phosphate transporters of Neurospora crassa; transcription regulated by inorganic phosphate concentrations and Pho4p; Sodium-phosphate symporter. Active in early growth phase (574 aa)
     
   
  0.842
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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