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ECM15 protein (Saccharomyces cerevisiae) - STRING interaction network
"ECM15" - Non-essential protein of unknown function, likely exists as tetramer, may be regulated by the binding of small-molecule ligands (possibly sulfate ions), may have a role in yeast cell-wall biogenesis in Saccharomyces cerevisiae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ECM15Non-essential protein of unknown function, likely exists as tetramer, may be regulated by the binding of small-molecule ligands (possibly sulfate ions), may have a role in yeast cell-wall biogenesis (104 aa)    
Predicted Functional Partners:
THI6
Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase; required for thiamine biosynthesis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern; Essential for thiamine biosynthesis. The kinase activity is involved in the salvage synthesis of TH-P from the thiazole (540 aa)
              0.560
ECM14
Putative metalloprotease with similarity to zinc carboxypeptidases; required for normal cell wall assembly; Probable carboxypeptidase that may be involved in cell wall organization and biogenesis (430 aa)
         
  0.558
YPL068C
Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and is induced in response to the DNA-damaging agent MMS (293 aa)
       
 
  0.532
ECM18
Protein of unknown function, similar to Rlp24p; May be involved in cell wall organization and biogenesis (453 aa)
         
  0.496
ECM34
Putative protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; May be involved in cell wall organization and biogenesis (170 aa)
           
  0.487
ECM21
Protein involved in regulating the endocytosis of plasma membrane proteins; identified as a substrate for ubiquitination by Rsp5p and deubiquitination by Ubp2p; promoter contains several Gcn4p binding elements; May be involved in cell wall organization and biogenesis (1117 aa)
           
  0.485
YGR219W
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF MRPL9/YGR220C (113 aa)
           
  0.447
YCR087W
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps uncharacterized gene YCR087C-A; YCR087W is not an essential gene (171 aa)
           
  0.447
ECM11
Non-essential protein apparently involved in meiosis, GFP fusion protein is present in discrete clusters in the nucleus throughout mitosis; may be involved in maintaining chromatin structure; May be involved in cell wall organization and biogenesis (302 aa)
           
  0.446
SMI1
Protein involved in the regulation of cell wall synthesis; proposed to be involved in coordinating cell cycle progression with cell wall integrity; Protein involved in the regulation of cell wall assembly and 1,3-beta-glucan synthesis, possibly through the transcriptional regulation of cell wall glucan and chitin synthesis (505 aa)
           
  0.441
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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