| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACT1 | FMP27 | YFL039C | YLR454W | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | 0.435 |
| ACT1 | IES2 | YFL039C | YNL215W | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | Ino eighty subunit 2; Protein that associates with the INO80 chromatin remodeling complex; associates with the INO80 complex under low-salt conditions; essential for growth under anaerobic conditions; protein abundance increases in response to DNA replication stress; Belongs to the IES2 family. | 0.999 |
| ACT1 | YBL086C | YFL039C | YBL086C | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | Uncharacterized protein YBL086C; Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery. | 0.793 |
| FMP27 | ACT1 | YLR454W | YFL039C | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | 0.435 |
| FMP27 | OSH3 | YLR454W | YHR073W | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Member of an oxysterol-binding protein family; this family has seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; contains FFAT motif; interacts with ER anchor Scs2p at patches at the plasma membrane; regulated by sterol binding; Belongs to the OSBP family. | 0.846 |
| FMP27 | YBL086C | YLR454W | YBL086C | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Uncharacterized protein YBL086C; Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery. | 0.963 |
| IES2 | ACT1 | YNL215W | YFL039C | Ino eighty subunit 2; Protein that associates with the INO80 chromatin remodeling complex; associates with the INO80 complex under low-salt conditions; essential for growth under anaerobic conditions; protein abundance increases in response to DNA replication stress; Belongs to the IES2 family. | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | 0.999 |
| IES2 | RGD2 | YNL215W | YFL047W | Ino eighty subunit 2; Protein that associates with the INO80 chromatin remodeling complex; associates with the INO80 complex under low-salt conditions; essential for growth under anaerobic conditions; protein abundance increases in response to DNA replication stress; Belongs to the IES2 family. | Rho-GTPase-activating protein RGD2; GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p; relocalizes from bud neck to cytoplasm upon DNA replication stress. | 0.694 |
| IES2 | YBL086C | YNL215W | YBL086C | Ino eighty subunit 2; Protein that associates with the INO80 chromatin remodeling complex; associates with the INO80 complex under low-salt conditions; essential for growth under anaerobic conditions; protein abundance increases in response to DNA replication stress; Belongs to the IES2 family. | Uncharacterized protein YBL086C; Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery. | 0.747 |
| LYS20 | YBL086C | YDL182W | YBL086C | Homocitrate synthase isozyme and functions in DNA repair; catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; LYS20 has a paralog, LYS21, that arose from the whole genome duplication; Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily. | Uncharacterized protein YBL086C; Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery. | 0.774 |
| OSH3 | FMP27 | YHR073W | YLR454W | Member of an oxysterol-binding protein family; this family has seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; contains FFAT motif; interacts with ER anchor Scs2p at patches at the plasma membrane; regulated by sterol binding; Belongs to the OSBP family. | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | 0.846 |
| OSH3 | YBL086C | YHR073W | YBL086C | Member of an oxysterol-binding protein family; this family has seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; contains FFAT motif; interacts with ER anchor Scs2p at patches at the plasma membrane; regulated by sterol binding; Belongs to the OSBP family. | Uncharacterized protein YBL086C; Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery. | 0.642 |
| RGD2 | IES2 | YFL047W | YNL215W | Rho-GTPase-activating protein RGD2; GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p; relocalizes from bud neck to cytoplasm upon DNA replication stress. | Ino eighty subunit 2; Protein that associates with the INO80 chromatin remodeling complex; associates with the INO80 complex under low-salt conditions; essential for growth under anaerobic conditions; protein abundance increases in response to DNA replication stress; Belongs to the IES2 family. | 0.694 |
| RGD2 | YBL086C | YFL047W | YBL086C | Rho-GTPase-activating protein RGD2; GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p; relocalizes from bud neck to cytoplasm upon DNA replication stress. | Uncharacterized protein YBL086C; Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery. | 0.694 |
| STU2 | YBL086C | YLR045C | YBL086C | Protein STU2; Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p; Belongs to the TOG/XMAP215 family. | Uncharacterized protein YBL086C; Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery. | 0.650 |
| YBL086C | ACT1 | YBL086C | YFL039C | Uncharacterized protein YBL086C; Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery. | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | 0.793 |
| YBL086C | FMP27 | YBL086C | YLR454W | Uncharacterized protein YBL086C; Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery. | Protein FMP27, mitochondrial; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | 0.963 |
| YBL086C | IES2 | YBL086C | YNL215W | Uncharacterized protein YBL086C; Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery. | Ino eighty subunit 2; Protein that associates with the INO80 chromatin remodeling complex; associates with the INO80 complex under low-salt conditions; essential for growth under anaerobic conditions; protein abundance increases in response to DNA replication stress; Belongs to the IES2 family. | 0.747 |
| YBL086C | LYS20 | YBL086C | YDL182W | Uncharacterized protein YBL086C; Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery. | Homocitrate synthase isozyme and functions in DNA repair; catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; LYS20 has a paralog, LYS21, that arose from the whole genome duplication; Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily. | 0.774 |
| YBL086C | OSH3 | YBL086C | YHR073W | Uncharacterized protein YBL086C; Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery. | Member of an oxysterol-binding protein family; this family has seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; contains FFAT motif; interacts with ER anchor Scs2p at patches at the plasma membrane; regulated by sterol binding; Belongs to the OSBP family. | 0.642 |
