Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MRP21Mitochondrial ribosomal protein of the small subunit; MRP21 exhibits genetic interactions with mutations in the COX2 and COX3 mRNA 5'-untranslated leader sequences. (177 aa)    
Predicted Functional Partners:
MRPS5
Mitochondrial ribosomal protein of the small subunit.
   
 0.999
MRP4
Mitochondrial ribosomal protein of the small subunit.
   
 0.999
RSM25
Mitochondrial ribosomal protein of the small subunit.
   
 0.999
MRPS12
37S ribosomal protein S12, mitochondrial; Mitochondrial protein; may interact with ribosomes based on co-purification experiments; similar to E. coli and human mitochondrial S12 ribosomal proteins; Belongs to the universal ribosomal protein uS12 family.
   
 0.999
MRPS16
Mitochondrial ribosomal protein of the small subunit.
   
 0.999
RSM18
Mitochondrial ribosomal protein of the small subunit; has similarity to E. coli S18 ribosomal protein.
   
 0.998
MRPS18
Mitochondrial ribosomal protein of the small subunit; essential for viability, unlike most other mitoribosomal proteins.
   
 0.998
RSM10
Mitochondrial ribosomal protein of the small subunit; has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins.
   
 0.997
MRPS28
Mitochondrial ribosomal protein of the small subunit.
   
 0.997
MRP17
Mitochondrial ribosomal protein of the small subunit; MRP17 exhibits genetic interactions with PET122, encoding a COX3-specific translational activator.
   
 0.997
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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